Description

(S)-(-)-1-(p-Tolyl)Ethylamine is a high-purity chiral amine building block of significant importance in asymmetric synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with defined stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require enantiomerically pure intermediates for active ingredient development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Catalyst Ligand Precursor: Used in the preparation of chiral ligands for transition metal catalysis, enabling highly enantioselective transformations.
• Agrochemical Synthesis: Employed in the production of chiral herbicides, fungicides, and pesticides where specific stereochemistry is critical for biological activity and environmental safety.
• Fine Chemical and Specialty Material Production: Serves as a building block for advanced materials, liquid crystals, and other performance chemicals requiring precise molecular architecture.
• Resolution Agent: Can be utilized as a chiral resolving agent for the separation of racemic mixtures of carboxylic acids or other compounds.

Basic Information

Product Name	(S)-(-)-1-(p-Tolyl)Ethylamine
CAS No.	27298-98-2
Molecular Formula	C9H13N
Molecular Weight	135.21 g/mol
Synonyms	(S)-(-)-1-(4-Methylphenyl)ethylamine; (S)-1-(p-Tolyl)ethanamine; (S)-α-Methyl-4-methylbenzylamine; (S)-(-)-α-Methyl-p-toluidine; (S)-1-(4-Methylphenyl)ethan-1-amine; (S)-p-Tolylethylamine; (S)-(-)-1-(4-Tolyl)ethylamine
EINECS	Contact for details

Quality Control

Our production of (S)-(-)-1-(p-Tolyl)Ethylamine adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by advanced analytical techniques including chiral HPLC, GC, and NMR. Certificates of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.