Description

Methyl 3,5-Bis(Trifluoromethyl)Benzoate is a high-value fluorinated aromatic ester, serving as a critical building block in advanced organic synthesis. Its significance lies in the unique electronic and steric properties imparted by the two trifluoromethyl groups, which are essential for modulating the activity and stability of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by manufacturers of specialty materials and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl groups enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in high-performance displays (LCDs).
• Organic Electronics: Employed in the synthesis of electron-deficient aromatic units for organic semiconductors, OLEDs, and photovoltaic materials.
• Catalyst Ligand Precursor: Useful for constructing sophisticated ligand frameworks in transition metal catalysis for fine chemical production.
• Advanced Polymer Monomer: Incorporated into specialty polymers to impart unique solubility, thermal stability, and chemical resistance properties.

Basic Information

Product Name	Methyl 3,5-Bis(Trifluoromethyl)Benzoate
CAS No.	26107-80-2
Molecular Formula	C11H6F6O2
Molecular Weight	284.16 g/mol
Synonyms	3,5-Bis(trifluoromethyl)benzoic acid methyl ester; Methyl 3,5-di(trifluoromethyl)benzoate; Benzoic acid, 3,5-bis(trifluoromethyl)-, methyl ester; Methyl α,α,α,α',α',α'-hexafluoro-3,5-xylylate; 3,5-Di(trifluoromethyl)phenyl methyl carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 3,5-Bis(Trifluoromethyl)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and sources of ignition. Due to the presence of fluoride/strong alkali reactive groups, ensure proper segregation from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.