Description

6-Fluoro-2,3-Dihydrobenzofuran-2-Carboxylic Acid is a high-value fluorinated heterocyclic building block essential for modern synthetic chemistry. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals, where the introduction of fluorine atoms is a key strategy for modulating biological activity and metabolic stability. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors engaged in the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine moiety enhances efficacy and environmental profile.
• Material Science Research: Serves as a precursor for developing novel fluorinated polymers and liquid crystals with unique properties.
• Organic Synthesis Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis due to its reactive carboxylic acid and fused ring system.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	6-Fluoro-2,3-Dihydrobenzofuran-2-Carboxylic Acid
CAS No.	26018-67-7
Molecular Formula	C9H7FO3
Molecular Weight	182.15 g/mol
Synonyms	6-Fluoro-2,3-dihydro-2-benzofurancarboxylic acid; 6-Fluoro-2,3-dihydrobenzofuran-2-carboxylic acid; 2,3-Dihydro-6-fluorobenzofuran-2-carboxylic acid; 6-Fluoro-2,3-dihydro-1-benzofuran-2-carboxylic acid; 6-Fluoro-2-carboxy-2,3-dihydrobenzofuran; 26018-67-7; 6-Fluoro-2,3-dihydrobenzo[b]furan-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Fluoro-2,3-Dihydrobenzofuran-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.