Description

6-Fluorobenzofuran-2-Carboxylic Acid is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is particularly significant for introducing the benzofuran scaffold with a fluorine substituent, which can dramatically alter the physicochemical and biological properties of target molecules. It is a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom enhances bioavailability and environmental stability.
• Material Science: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its conjugated structure and fluorine moiety.
• Chemical Synthesis Building Block: Acts as a versatile starting material for further functionalization, including amide coupling, esterification, and reduction reactions to create diverse chemical libraries.

Basic Information

Product Name	6-Fluorobenzofuran-2-Carboxylic Acid
CAS No.	26018-66-6
Molecular Formula	C9H5FO3
Molecular Weight	180.13 g/mol
Synonyms	6-Fluoro-1-benzofuran-2-carboxylic acid; 6-Fluoro-2-benzofurancarboxylic acid; 2-Benzofurancarboxylic acid, 6-fluoro-; 6-Fluorobenzofuran-2-carboxylic acid; 6-Fluoro-2-carboxybenzofuran; 26018-66-6; 6-Fluorobenzofurane-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Fluorobenzofuran-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, NMR, and other relevant spectroscopic methods. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.