Description

H-[15N]Ala-Oh is a stable isotope-labeled analog of the amino acid alanine, where the nitrogen atom is enriched with the 15N isotope. This compound is essential for advanced research and analytical applications requiring precise molecular tracking and quantification. It is primarily utilized by scientists and manufacturers in the pharmaceutical, biotechnology, and life science research sectors for applications such as metabolic pathway studies, protein NMR spectroscopy, and as an internal standard in mass spectrometry.

Application

• NMR Spectroscopy: Used as a 15N-labeled building block for protein and peptide structure determination and dynamics studies.
• Mass Spectrometry: Serves as a critical internal standard for the accurate quantification of alanine and related metabolites in complex biological samples.
• Metabolic Research: Employed in tracer studies to investigate amino acid metabolism, protein synthesis rates, and metabolic flux analysis.
• Pharmaceutical Development: Utilized in the research and development of novel therapeutics, including the study of drug metabolism and pharmacokinetics (DMPK).
• Biochemical Reagent: Acts as a labeled precursor for the synthesis of more complex isotopically labeled peptides and biochemical compounds.
• Nutritional Science: Applied in research to study protein turnover, amino acid requirements, and metabolic disorders.

Basic Information

Product Name	H-[15N]Ala-Oh
CAS No.	25713-23-9
Molecular Formula	C₃H₆¹⁵NO₂
Molecular Weight	90.08 g/mol (for 15N labeled)
Synonyms	L-Alanine-15N; (S)-2-Amino(15N)propanoic acid; Alanine-15N; H-Ala(15N)-OH; 15N-L-Alanine; (2S)-2-Azanyl(15N)propanoic acid; Isotope-labeled alanine; 15N labeled alanine
EINECS	Contact for details

Quality Control

Our H-[15N]Ala-Oh is produced under strict quality management systems to ensure the highest isotopic and chemical purity for research applications. Each batch is thoroughly characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry to confirm identity, isotopic enrichment (typically >98 atom % 15N), and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccated conditions or storage under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Enrichment (MS)	≥98 atom % 15N
Optical Rotation	Specific range provided on COA
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.