Description

Trimipramine Mesilate is the mesylate salt form of the tricyclic antidepressant compound trimipramine. This active pharmaceutical ingredient (API) is a critical component in the formulation of antidepressant medications, valued for its stability and bioavailability. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of central nervous system (CNS) therapeutics.

Application

• Pharmaceutical API: Primary use as the active ingredient in the manufacture of antidepressant drug formulations.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Clinical Research: Utilized in preclinical and clinical studies investigating the efficacy and pharmacokinetics of tricyclic antidepressants.
• Generic Drug Production: Essential for companies developing bioequivalent generic versions of branded trimipramine medications.
• Pharmacological Studies: Used in academic and industrial research to study the mechanism of action of antidepressant drugs.

Basic Information

Product Name	Trimipramine Mesilate
CAS No.	25332-13-2
Molecular Formula	C₂₀H₂₆N₂ • CH₄O₃S
Molecular Weight	410.55 g/mol
Synonyms	Trimipramine Mesylate; Trimipramine Methanesulfonate; 5-(3-Dimethylamino-2-methylpropyl)-10,11-dihydro-5H-dibenzo[b,f]azepine methanesulfonate; Surmontil (brand name salt); RP 7162; Trimipramine Monomethanesulfonate; Trimipramine Metilsulfate
EINECS	Contact for details

Quality Control

Our Trimipramine Mesilate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.