Description

2-Nitro-6-(Trifluoromethyl)Benzoic Acid is a high-value, multi-functional aromatic building block characterized by its nitro and trifluoromethyl substituents. This compound is essential for synthesizing advanced intermediates where electronic modulation and enhanced lipophilicity are required. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a benzoic acid scaffold with electron-withdrawing groups.
• Agrochemical Synthesis: Used in the development of new herbicides and pesticides, where the trifluoromethyl group often improves biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, contributing to the molecular architecture of dyes and charge-transport layers.
• Organic Synthesis & Research: A versatile reagent for introducing nitro and trifluoromethyl functionalities into complex molecules in academic and industrial R&D settings.
• Coordination Chemistry: Can act as a ligand or a precursor to ligands for metal-organic frameworks (MOFs) and catalysts.

Basic Information

Product Name	2-Nitro-6-(Trifluoromethyl)Benzoic Acid
CAS No.	24821-18-9
Molecular Formula	C8H4F3NO4
Molecular Weight	235.12 g/mol
Synonyms	6-(Trifluoromethyl)-2-nitrobenzoic acid; 2-Nitro-α,α,α-trifluoro-m-toluic acid; Benzoic acid, 2-nitro-6-(trifluoromethyl)-; m-Trifluoromethyl-2-nitrobenzoic acid; 2-Nitro-6-trifluoromethylbenzoic acid; 2-Nitro-6-(trifluoromethyl)benzenecarboxylic acid; 24821-18-9 (CAS)
EINECS	Contact for details

Quality Control

Our 2-Nitro-6-(Trifluoromethyl)Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets precise customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.