Description

Nomifensine Maleate is a high-purity organic salt compound, specifically the maleate salt of nomifensine. This compound is of significant interest in advanced pharmaceutical research and development due to its specific pharmacological profile. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in neuroscience and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Reference Standard: Serves as a critical certified reference material (CRM) for quality control and analytical method development in drug manufacturing.
• Neuroscience Research: Used as a biochemical tool in preclinical studies to investigate neurotransmitter systems, particularly those involving dopamine and norepinephrine reuptake inhibition.
• Active Pharmaceutical Ingredient (API) Intermediate: Acts as a key synthetic precursor or intermediate in the production of specialized neuropharmacological agents.
• Metabolite Studies: Employed in the development and validation of bioanalytical assays for pharmacokinetic and metabolic pathway analysis.
• Academic Research: Utilized in university and institutional labs for fundamental pharmacological and medicinal chemistry research projects.

Basic Information

Product Name	Nomifensine Maleate
CAS No.	24526-64-5
Molecular Formula	C16H18N2 • C4H4O4
Molecular Weight	354.38 g/mol
Synonyms	8-Amino-1,2,3,4-tetrahydro-2-methyl-4-phenylisoquinoline maleate; Nomifensine hydrogen maleate; Merital maleate; Alival maleate; 4-Phenyl-1,2,3,4-tetrahydro-2-methyl-8-isoquinolinamine (Z)-2-butenedioate; (±)-Nomifensine maleate
EINECS	Contact for details

Quality Control

Our Nomifensine Maleate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.