Description

L-Cysteine, [35S] CAS NO 24321-12-8 is a sulfur-35 radiolabeled derivative of the essential amino acid L-Cysteine, a critical building block for proteins and a key component in cellular redox biochemistry. This isotopically labeled compound is indispensable for advanced metabolic and pharmacokinetic studies, enabling precise tracking of sulfur-containing biomolecules in complex biological systems. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic developers engaged in tracer studies, drug metabolism research, and biochemical pathway analysis.

Application

• Biochemical Tracer Studies: Used to trace the metabolic fate and incorporation of sulfur in proteins, peptides (like glutathione), and coenzymes.
• Drug Metabolism and Pharmacokinetics (DMPK): A vital tool for studying the absorption, distribution, metabolism, and excretion (ADME) of sulfur-containing pharmaceutical compounds.
• Proteomics and Protein Turnover Research: Facilitates the study of protein synthesis, degradation rates, and post-translational modifications involving cysteine residues.
• Mechanistic Toxicology Studies: Investigates the role of cysteine and related thiols in detoxification pathways and chemical toxicity mechanisms.
• Diagnostic Agent Development: Serves as a precursor for radiolabeling diagnostic probes and imaging agents used in nuclear medicine.
• Nutritional and Metabolic Research: Explores sulfur amino acid metabolism, homocysteine cycles, and related nutritional biochemistry.

Basic Information

Product Name	L-Cysteine, [35S]
CAS No.	24321-12-8
Molecular Formula	C3H7NO2S* (*[35S])
Molecular Weight	~122.16 g/mol (for unlabeled form)
Synonyms	(2R)-2-Amino-3-sulfanyl-[35S]propanoic acid; L-Cysteine-35S; Radiolabeled L-Cysteine; Cysteine-35S; (R)-2-Amino-3-mercapto[35S]propionic acid; [35S]-L-Cysteine; 3-Sulfanyl-L-alanine-35S; β-Mercapto[35S]alanine
EINECS	Contact for details

Quality Control

Every batch of our L-Cysteine, [35S] is produced and controlled under stringent quality management systems to ensure the highest standards of radiochemical purity, chemical purity, and specific activity. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing critical parameters such as radiochemical purity (by HPLC), specific activity, chemical purity, and solvent content. Our quality commitment aligns with the rigorous demands of research and pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at or below -20°C. This product is strictly light-sensitive (protect from all light exposure) and easily oxidized (store under inert atmosphere). Appropriate shielding and handling procedures for radioactive materials must be followed in accordance with local and international regulations.

Specification

Item	Specification
Appearance	White to off-white solid or solution (as specified)
Identification (IR/HPLC)	Conforms to reference standard
Radiochemical Purity (HPLC)	≥ 95%
Chemical Purity (HPLC)	≥ 98%
Specific Activity	Customized to order (mCi/mmol)
Solvent (if supplied as solution)	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.