Description

Mianserin CAS NO 24219-97-4 is a tetracyclic antidepressant compound belonging to the piperazinoazepine class. It is a high-purity active pharmaceutical ingredient (API) of significant importance for research and development in the pharmaceutical industry. This compound is primarily utilized by pharmaceutical manufacturers, research institutions, and chemical suppliers focused on neuropharmacology and drug discovery.

Application

• Pharmaceutical Active Ingredient (API): Core component in the formulation of antidepressant medications.
• Reference Standard: Used as a certified standard in analytical laboratories for quality control and method validation.
• Biochemical Research: A vital tool for studying neurotransmitter systems, particularly histamine (H1) and serotonin (5-HT) receptors.
• Preclinical & Clinical Studies: Serves as a key material in pharmacological research for investigating mechanisms of action and therapeutic efficacy.
• Process Development: Used in the development and optimization of synthetic routes for pharmaceutical manufacturing.
• Impurity Profiling: Employed as a marker in the identification and quantification of related substances in drug products.

Basic Information

Product Name	Mianserin
CAS No.	24219-97-4
Molecular Formula	C18H20N2
Molecular Weight	264.37 g/mol
Synonyms	1,2,3,4,10,14b-Hexahydro-2-methyldibenzo[c,f]pyrazino[1,2-a]azepine; Mianserin Hydrochloride (salt form); Tolvin; Bolvidon; Norval; Athymil; GB-94; Org GB 94; 6-Azabenzo[a]cyclohepta[cd]phenalene derivative
EINECS	246-125-8

Quality Control

Our Mianserin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing parameters such as assay, related substances, residual solvents, and identification.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.