Description

Glutamic Acid, L-, [1-14C] is a high-purity, carbon-14 labeled isotopologue of L-Glutamic acid, a fundamental amino acid. This product is specifically designed for advanced research requiring precise metabolic and biochemical pathway tracing. It is an essential tool for scientists in pharmaceutical development, nutritional biochemistry, and plant physiology who require reliable radiolabeled compounds for autoradiography, LC-MS/MS, and other sensitive analytical techniques.

Application

• Metabolic Pathway Analysis: Tracing the incorporation and fate of glutamic acid in central metabolic cycles such as the citric acid cycle and amino acid synthesis.
• Drug Metabolism and Pharmacokinetics (DMPK): Serving as a radiolabeled tracer in ADME (Absorption, Distribution, Metabolism, Excretion) studies for pharmaceutical candidates.
• Neurochemical Research: Investigating the role of glutamate as a neurotransmitter, including studies on receptor binding, uptake, and synaptic function.
• Plant and Microbial Physiology: Studying nitrogen assimilation, amino acid metabolism, and protein synthesis in biological systems.
• Biochemical Assay Development: Use as an internal standard or tracer in quantitative analytical methods like liquid chromatography-mass spectrometry (LC-MS).
• Nutritional Science Research: Exploring glutamic acid metabolism, protein turnover, and its functional role in human and animal nutrition.

Basic Information

Product Name	Glutamic Acid, L-, [1-14C]
CAS No.	24016-47-5
Molecular Formula	C5H914CNO4
Molecular Weight	~150.1 g/mol (based on 14C)
Synonyms	(2S)-2-Aminopentanedioic-1-14C acid; L-Glutamic-1-14C acid; (S)-2-Aminopentanedioic-1-14C acid; L-Glu-1-14C; Glutamic acid (L-) (1-14C); [1-14C]-L-Glutamic acid; Carbon-14 labeled L-glutamate
EINECS	Contact for details

Quality Control

Every batch of our carbon-14 labeled L-Glutamic Acid is manufactured and analyzed under strict quality systems to ensure high chemical, radiochemical, and enantiomeric purity. We provide comprehensive Certificates of Analysis (COA) detailing specific activity, purity by HPLC, radiochemical purity, and chiral purity to confirm the absence of the D-isomer. Our quality commitment supports research requiring reproducible and reliable tracer data for regulatory submissions and critical studies.

Storage

Preserve in a tightly closed container, protected from light. Store at or below -20°C. This product is intended for research use only by trained personnel in appropriately equipped laboratories following all applicable radiation safety guidelines and regulations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR / NMR)	Conforms to structure
Specific Activity	50-60 mCi/mmol (Contact for specific batch data)
Chemical Purity (HPLC)	≥ 98%
Radiochemical Purity (HPLC)	≥ 97%
Chiral Purity (HPLC)	≥ 99% L-isomer
Solubility	Soluble in dilute acid or alkali, slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.