Description

(1R,2S)-2-Amino-1,2-Diphenylethanol is a high-purity chiral amino alcohol building block of significant importance in asymmetric synthesis. Its value lies in its utility as a versatile ligand for metal catalysts and as a precursor for chiral auxiliaries and pharmaceutical intermediates. This compound is essential for research and production in the pharmaceutical, agrochemical, and fine chemical industries, where precise stereochemical control is paramount.

Application

• Asymmetric Catalysis: Employed as a chiral ligand or modifier in transition metal-catalyzed reactions such as hydrogenations, hydrosilylations, and epoxidations.
• Pharmaceutical Intermediates: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and cardiovascular diseases.
• Chiral Auxiliary/Resolving Agent: Used for the resolution of racemic mixtures and as a building block for constructing other chiral auxiliaries.
• Agrochemical Synthesis: Integral to the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and process chemistry optimization.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.

Basic Information

Item	Details
Product Name	(1R,2S)-2-Amino-1,2-Diphenylethanol
CAS No.	23190-16-1
Molecular Formula	C14H15NO
Molecular Weight	213.28 g/mol
Synonyms	(1R,2S)-(-)-2-Amino-1,2-diphenylethanol; (-)-cis-1-Amino-2-indanol; (1R,2S)-1,2-Diphenyl-2-aminoethanol; (1R,2S)-(-)-2-Amino-1,2-diphenylethanol; D-phenylglycinol (stereospecific); (R,S)-(-)-2-Amino-1,2-diphenylethanol; (1R,2S)-Amino alcohol; NSC 403825
EINECS	Contact for details

Quality Control

Our (1R,2S)-2-Amino-1,2-Diphenylethanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure compliance with high-purity standards, including chiral purity assessment. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), enantiomeric excess, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 1.0 %
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.