Description

L-2-Thienylalanine is a non-proteinogenic amino acid derivative featuring a thiophene ring, a structural motif of significant interest in medicinal chemistry. This compound serves as a crucial chiral building block for the synthesis of novel pharmaceuticals and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, particularly for developing enzyme inhibitors, peptide mimetics, and diagnostic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs).
• Peptidomimetics: Used to incorporate the thienyl moiety into peptide backbones to enhance metabolic stability and modulate biological activity.
• Enzyme Inhibitor Design: Serves as a core structure or side-chain analog in the design of inhibitors for various enzymes.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds or probes for studying biological pathways and target engagement.
• Asymmetric Synthesis: Utilized as a starting material or auxiliary in stereoselective synthetic routes.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers with unique electronic or optical properties.

Basic Information

Product Name	L-2-Thienylalanine
CAS No.	22951-96-8
Molecular Formula	C7H9NO2S
Molecular Weight	171.22 g/mol
Synonyms	(S)-2-Amino-3-(thiophen-2-yl)propanoic acid; L-2-Thienylalanine; L-β-(2-Thienyl)alanine; (S)-2-Amino-3-(2-thienyl)propionic acid; L-Thien-2-yl-alanine; 2-Thienyl-L-alanine; L-α-Amino-β-(2-thienyl)propionic acid; NSC 143491
EINECS	Contact for details

Quality Control

Our L-2-Thienylalanine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results for identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.