Description

L-Homocysteine-D-Penicillamine Disulfide is a specialized heterodimeric disulfide compound of significant interest in biochemical and pharmaceutical research. This molecule combines structural elements of the amino acid homocysteine and the chelating agent D-penicillamine, creating a unique tool for studying redox biology, metal chelation, and enzyme inhibition. It is primarily sought after by research institutions and pharmaceutical developers working in areas such as metabolic pathway analysis, antioxidant mechanisms, and the development of novel therapeutic agents. Its distinct structure makes it a critical reference standard and intermediate for advanced life science applications.

Application

• Biochemical Research: Used as a reference standard and substrate in studies of homocysteine metabolism, transsulfuration pathways, and redox regulation.
• Pharmaceutical Development: Serves as a key intermediate or building block in the synthesis of potential therapeutic agents targeting cardiovascular or neurological disorders.
• Enzymology Studies: Employed to investigate the activity and inhibition of enzymes like cystathionine β-synthase (CBS) and other pyridoxal phosphate-dependent enzymes.
• Antioxidant Research: Acts as a model compound to study the antioxidant properties and radical scavenging activities of disulfide-containing molecules.
• Chelation Chemistry: Utilized in research exploring the chelation of heavy metals due to the penicillamine moiety, relevant for detoxification studies.
• Metabolite Analysis: Functions as a calibration standard in analytical methods (e.g., HPLC, LC-MS) for the accurate quantification of homocysteine and related thiol/disulfide species in biological samples.

Basic Information

Product Name	L-Homocysteine-D-Penicillamine Disulfide
CAS No.	22801-31-6
Molecular Formula	C11H20N2O4S2
Molecular Weight	308.42 g/mol
Synonyms	L-HomoCys-D-Pen disulfide; (R)-2-Amino-4-((R)-3-amino-3-carboxy-2-methylpropyl)disulfanyl)butanoic acid; Homocysteine-Penicillamine Mixed Disulfide; D-Penicillamine-L-Homocysteine Disulfide; Hcy-Pen; L-Hcy-D-Pen; Mixed Disulfide of Homocysteine and Penicillamine; 3,3'-Dithiobis(2-aminobutanoic acid) derivative
EINECS	Contact for details

Quality Control

Our L-Homocysteine-D-Penicillamine Disulfide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment, chiral purity verification, and identity confirmation by spectroscopic methods. We provide comprehensive Certificates of Analysis (COA) detailing all specifications, ensuring traceability and compliance with research-grade standards. Our commitment to quality guarantees material integrity for your most sensitive applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (by chiral HPLC)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.