Description

3-Chloro-10,11-Dihydro-N,n-Dimethyl-5H-Dibenzo[A,D]Cycloheptene-5-(1-Propanamine) is a high-purity, advanced pharmaceutical intermediate with a complex tricyclic structure. This compound is critical for research and development in medicinal chemistry, particularly for synthesizing novel therapeutic agents targeting the central nervous system. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel tricyclic compounds with potential pharmacological activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new drug candidates, particularly for neurological and psychiatric disorders.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of complex target molecules.
• Academic Research: Utilized in university and institutional labs for studying organic synthesis methodologies and heterocyclic chemistry.

Basic Information

Product Name	3-Chloro-10,11-Dihydro-N,n-Dimethyl-5H-Dibenzo[A,D]Cycloheptene-5-(1-Propanamine)
CAS No.	22725-40-2
Molecular Formula	C20H24ClN
Molecular Weight	313.87 g/mol
Synonyms	3-Chloroamitriptyline; 3-Chloro-10,11-dihydro-N,N-dimethyl-5H-dibenzo[a,d]cycloheptene-5-propanamine; 3-Chloro-10,11-dihydro-N,N-dimethyl-5H-dibenzo[a,d]cycloheptene-δ5,γ-propylamine; 3-Chloro-5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene; 3-Chlorodihydroamitriptyline; 3-Cl-Amitriptyline; 22725-40-2
EINECS	Contact for details

Quality Control

Our 3-Chloro-10,11-Dihydro-N,n-Dimethyl-5H-Dibenzo[A,D]Cycloheptene-5-(1-Propanamine) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.