Description

1-O,2-O:3-O,5-o-Dibenzylidene-α-D-Glucofuranose Acetate is a protected carbohydrate derivative, specifically a benzylidene acetal of a glucofuranose core with an acetate group. This compound is a crucial chiral intermediate and protecting group reagent in sophisticated organic synthesis, valued for its ability to impart stereochemical control. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of nucleoside analogs, complex sugars, and other bioactive molecules where precise manipulation of hydroxyl groups is required.

Application

• Chiral Intermediate for Nucleoside Synthesis: Serves as a key building block in the multi-step synthesis of modified nucleosides and nucleotides with potential antiviral or anticancer activity.
• Protecting Group Reagent in Carbohydrate Chemistry: Used to selectively protect specific hydroxyl groups on sugar molecules, enabling controlled functionalization for the synthesis of oligosaccharides and glycoconjugates.
• Precursor for Specialty Ligands and Catalysts: Acts as a starting material for the preparation of chiral ligands used in asymmetric catalysis and molecular recognition.
• Research & Development of Glycomimetics: Employed in academic and industrial R&D to create sugar mimics for probing biological processes or developing new therapeutics.
• Synthesis of Complex Natural Products: Utilized in the total synthesis of natural products containing complex, stereodefined carbohydrate subunits.

Basic Information

Product Name	1-O,2-O:3-O,5-o-Dibenzylidene-α-D-Glucofuranose Acetate
CAS No.	22154-72-9
Molecular Formula	C22H22O7
Molecular Weight	398.41 g/mol
Synonyms	1,2:3,5-Di-O-benzylidene-α-D-glucofuranose 6-acetate; Di-O-benzylidene-α-D-glucofuranose acetate; 1,2:3,5-Di-O-benzylidene-α-D-glucofuranose 6-O-acetate; 6-O-Acetyl-1,2:3,5-di-O-benzylidene-α-D-glucofuranose; α-D-Glucofuranose, 1,2:3,5-bis-O-(phenylmethylene)-, 6-acetate; Acetylated Di-benzylidene Glucose; Protected Glucofuranose Acetate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of 1-O,2-O:3-O,5-o-Dibenzylidene-α-D-Glucofuranose Acetate is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific batch results are available upon request. We adhere to strict quality management protocols to support our customers' research and cGMP development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.