Description

Daledalin CAS NO 22136-27-2 is a selective and potent norepinephrine reuptake inhibitor (NRI) belonging to the class of tricyclic antidepressants. This compound is of significant interest in pharmaceutical research and development for its specific neurochemical activity. It serves as a critical intermediate and reference standard for scientists developing and analyzing novel therapeutic agents targeting depression and related central nervous system disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced antidepressant drug candidates.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control (QC/QA) of related pharmaceutical products.
• Biochemical Research: Employed in neuroscience studies to investigate the mechanisms of norepinephrine reuptake and its role in mood regulation.
• Preclinical Development: Utilized in pharmacological and toxicological studies during the early stages of drug discovery.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structure for creating new chemical entities with improved efficacy and safety profiles.

Basic Information

Product Name	Daledalin
CAS No.	22136-27-2
Molecular Formula	C18H20N2
Molecular Weight	264.37 g/mol
Synonyms	Daledaline; UK-3557-15; 2,3,4,9-Tetrahydro-2-methyl-1H-dibenz[3,4:6,7]cyclohepta[1,2-c]pyridine; 2-Methyl-2,3,4,9-tetrahydro-1H-dibenz[3,4:6,7]cyclohepta[1,2-c]pyridine; UK 3557; UK3557
EINECS	Contact for details

Quality Control

Our Daledalin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via techniques such as HPLC, NMR, and mass spectrometry. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.