Description

10,11-Dihydro-N,5-Dimethyl-5H-Dibenz[B,F]Azepin-10-Amine Hydrochloride is a high-purity pharmaceutical intermediate and organic building block. This compound is critical for research and development in medicinal chemistry, particularly for the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions engaged in drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of tricyclic antidepressant analogs and other central nervous system (CNS) active compounds.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities.
• Active Pharmaceutical Ingredient (API) Development: Used in the development and scale-up processes for potential new APIs targeting neurological pathways.
• Biochemical Research: Employed as a reference standard or ligand in biochemical assays and receptor binding studies.
• Custom Synthesis: A starting material for the custom synthesis of specialized derivatives and analogs for client-specific research projects.

Basic Information

Product Name	10,11-Dihydro-N,5-Dimethyl-5H-Dibenz[B,F]Azepin-10-Amine Hydrochloride
CAS No.	21737-55-3
Molecular Formula	C17H19N2·HCl
Molecular Weight	296.81 g/mol
Synonyms	10,11-Dihydro-N,5-dimethyl-5H-dibenzo[b,f]azepin-10-amine hydrochloride; Desipramine Impurity C; Desmethylimipramine Hydrochloride; 5H-Dibenz[b,f]azepine-10-amine, 10,11-dihydro-N,5-dimethyl-, hydrochloride; Norimipramine Hydrochloride; G-35020; NSC 114495; DMI Hydrochloride
EINECS	Contact for details

Quality Control

Our 10,11-Dihydro-N,5-Dimethyl-5H-Dibenz[B,F]Azepin-10-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets stringent specifications for pharmaceutical research. Certificates of Analysis (COA) documenting all test results are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.