Description

(1S,3R)-3-Hydroxycyclohexane-1-Carboxylic Acid is a high-purity chiral building block and key intermediate in organic synthesis. Its defined stereochemistry and bifunctional nature make it a valuable scaffold for constructing complex molecules with precise spatial orientation. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Asymmetric Synthesis: Used as a starting material or resolving agent in stereoselective reactions to produce enantiomerically pure compounds.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric catalysis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic and R&D: A valuable tool in medicinal chemistry and synthetic organic chemistry research for exploring new reaction pathways.
• Peptidomimetics: The carboxylic acid and hydroxyl groups make it a suitable building block for non-natural amino acids and peptide analogs.

Basic Information

Product Name	(1S,3R)-3-Hydroxycyclohexane-1-Carboxylic Acid
CAS No.	21531-45-3
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	(1S,3R)-3-Hydroxycyclohexanecarboxylic Acid; (1S,3R)-3-Hydroxy-1-cyclohexanecarboxylic Acid; trans-3-Hydroxycyclohexanecarboxylic Acid; (1S,3R)-HCCA; trans-HCCA; (1S,3R)-3-Hydroxycyclohexylcarboxylic Acid; 3-Hydroxy-trans-cyclohexanecarboxylic Acid; (1S,3R)-3-Hydroxy-cyclohexanecarbonsäure (German)
EINECS	Contact for details

Quality Control

Our (1S,3R)-3-Hydroxycyclohexane-1-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency, meeting the stringent requirements of pharmaceutical R&D and cGMP starting material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.