Description

4-Aminobenzoic Acid, [Carboxyl-14C] is a carbon-14 labeled derivative of para-aminobenzoic acid (PABA), a key biochemical intermediate. This radiolabeled compound is essential for precise metabolic and pharmacokinetic studies, enabling researchers to track the fate of molecules in complex biological systems with high sensitivity. It is a critical tool for scientists in pharmaceutical R&D, agrochemical development, and biochemical research who require reliable tracers for absorption, distribution, metabolism, and excretion (ADME) studies.

Application

• Drug Metabolism and Pharmacokinetics (DMPK): As a radiolabeled tracer in ADME studies for novel pharmaceutical compounds.
• Biochemical Pathway Analysis: Tracing the metabolic fate of PABA and related compounds in microbial, plant, or mammalian systems.
• Agrochemical Research: Investigating the uptake, translocation, and degradation of agrochemicals in environmental and biological samples.
• Vitamin Biosynthesis Studies: Research into folate (vitamin B9) synthesis pathways in various organisms.
• Protein Labeling & Conjugation: Utilizing the carboxyl-14C group for radiolabeling biomolecules for binding and interaction assays.
• Environmental Fate Studies: Monitoring the biodegradation and environmental persistence of chemical substances.

Basic Information

Product Name	4-Aminobenzoic Acid, [Carboxyl-14C]
CAS No.	21482-31-5
Molecular Formula	C7H714CNO2
Molecular Weight	~139.1 g/mol (exact mass depends on 14C enrichment)
Synonyms	p-Aminobenzoic Acid-carboxy-14C; PABA-carboxy-14C; 4-Amino[carboxy-14C]benzoic Acid; Vitamin BX (labeled); Benzoic acid, 4-amino-, carboxy-14C-; [carboxy-14C]-PABA; 4-14C-Carboxy-aniline
EINECS	Contact for details

Quality Control

Every batch of our carbon-14 labeled materials is produced and analyzed under strict quality systems to ensure radiochemical purity, chemical purity, and specific activity meet the exacting standards required for research. Comprehensive analysis via HPLC with radiometric detection is standard. A detailed Certificate of Analysis (COA) is provided with each shipment, specifying batch-specific data including purity, activity, and solvent composition.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures (typically 2-8°C or as specified on the label) in a designated, secure area for radioactive materials. This product is hygroscopic (moisture-sensitive); ensure containers are sealed properly after use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid or solution (as specified)
Identification (IR/HPLC)	Conforms to reference standard
Radiochemical Purity (HPLC)	≥ 95% to ≥ 98%
Chemical Purity (HPLC)	≥ 95%
Specific Activity	Customizable (mCi/mmol range)
Solvent (if supplied as solution)	Ethanol, Water, or other specified solvent

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.