Description

Dimethyl[3,3,3-Trifluoro-1-Oxo-2-(Trifluoromethyl)Propyl]Phosphine is a specialized organophosphorus compound featuring a unique trifluoromethylated β-ketophosphine structure. This compound is valued for its role as a versatile building block and ligand in advanced synthetic chemistry, particularly in the development of pharmaceuticals and agrochemicals. It is essential for researchers and manufacturers in fine chemical synthesis, catalysis, and materials science who require high-purity, reactive intermediates for creating complex, fluorinated molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those incorporating fluorine for enhanced metabolic stability and bioavailability.
• Catalyst Ligand: Serves as a ligand in transition metal catalysis for cross-coupling and other asymmetric synthesis reactions, leveraging its electron-donating properties.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides where the trifluoromethyl group imparts improved activity and environmental profile.
• Fine Chemical Building Block: Employed in organic synthesis for constructing complex, fluorinated organic molecules in research and development.
• Material Science Research: Investigated for the development of novel fluorinated polymers and advanced materials with specific electronic or surface properties.

Basic Information

Product Name	Dimethyl[3,3,3-Trifluoro-1-Oxo-2-(Trifluoromethyl)Propyl]Phosphine
CAS No.	20336-17-8
Molecular Formula	C7H7F6OP
Molecular Weight	252.10 g/mol
Synonyms	1,1,1,5,5,5-Hexafluoro-4-oxo-3-(dimethylphosphino)pentane; 3,3,3-Trifluoro-1-oxo-2-(trifluoromethyl)propyl dimethylphosphine; Dimethyl(3,3,3-trifluoro-1-oxo-2-(trifluoromethyl)propyl)phosphane; (3,3,3-Trifluoro-1-oxo-2-(trifluoromethyl)propyl)dimethylphosphine; Hexafluoroacetylacetone dimethylphosphine adduct
EINECS	Contact for details

Quality Control

Our Dimethyl[3,3,3-Trifluoro-1-Oxo-2-(Trifluoromethyl)Propyl]Phosphine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, GC, and HPLC, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should be kept sealed and only opened in a controlled environment. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Purity (NMR)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.