Description

Tris(Pentafluorophenyl)Phosphine Oxide is a highly fluorinated organophosphorus compound that serves as a versatile and valuable ligand precursor and catalyst component. Its unique electronic properties, imparted by the electron-withdrawing pentafluorophenyl groups, make it a critical reagent in advanced synthetic chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors, particularly for developing novel catalysts and facilitating challenging cross-coupling reactions.

Application

• Catalyst Ligand Precursor: Used in the synthesis of highly active palladium and other transition metal catalysts for cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira).
• Pharmaceutical Intermediate Synthesis: Facilitates the construction of complex molecular architectures in active pharmaceutical ingredient (API) development.
• Agrochemical Research: Employed in the creation of novel herbicides, fungicides, and insecticides requiring fluorinated components.
• Material Science: Acts as a building block or additive in the development of advanced polymers, coatings, and electronic materials.
• Organic Synthesis Reagent: Utilized as a stabilizing ligand or promoter in various organometallic and organic transformations.
• Academic & Industrial R&D: A key tool for chemists exploring new catalytic systems and reaction methodologies.

Basic Information

Product Name	Tris(Pentafluorophenyl)Phosphine Oxide
CAS No.	2729-11-5
Molecular Formula	C₁₈F₁₅OP
Molecular Weight	584.13 g/mol
Synonyms	Tris(pentafluorophenyl)phosphine oxide; Phosphine oxide, tris(pentafluorophenyl)-; (Pentafluorophenyl)triphenylphosphine oxide (common misnomer); TPOP; F15-TPPO; Tris(2,3,5,6-tetrafluoro-4-fluorophenyl)phosphine oxide; Tris(perfluorophenyl)phosphine oxide
EINECS	Contact for details

Quality Control

Our Tris(Pentafluorophenyl)Phosphine Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with high-purity reagent standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use or storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.