Description

(+)-Muscarine Chloride CAS NO 2303-35-7 is a high-purity, pharmacologically active alkaloid salt, serving as a critical reference standard and research chemical. Its primary value lies in its potent and selective agonism of muscarinic acetylcholine receptors (mAChRs), making it indispensable for neurological and pharmacological studies. This product is essential for researchers and developers in pharmaceutical R&D, academic neuroscience, and biochemical assay development, where precise receptor interaction studies are required.

Application

• Pharmacological Research: As a selective muscarinic receptor agonist for studying cholinergic signaling pathways, receptor subtypes (M1-M5), and related physiological effects.
• Neuroscience Studies: For investigating the role of the parasympathetic nervous system, synaptic transmission, and cognitive functions in experimental models.
• Drug Discovery & Development: Used as a reference compound in high-throughput screening (HTS) assays to identify and characterize new mAChR modulators or antagonists.
• Biochemical Tool: Employed in in vitro and ex vivo tissue bath experiments to induce controlled muscarinic responses for physiological research.
• Toxicology & Safety Assessment: Serves as a control substance in studies examining the effects of cholinergic agents and related toxicities.
• Academic & Educational Use: A key reagent for university laboratories and teaching institutions focused on neuropharmacology and medicinal chemistry.

Basic Information

Item	Detail
Product Name	(+)-Muscarine Chloride
CAS No.	2303-35-7
Molecular Formula	C9H20ClNO2
Molecular Weight	209.72 g/mol
Synonyms	(+)-Muscarine Chloride; Muscarine Chloride; L-(+)-Muscarine Chloride; (2S,4R,5S)-4-Hydroxy-5-methyl-2-(trimethylammonio)methyl-1,3-dioxolane Chloride; Muscarine; Agaric acid; Oxyde de choline muscarinique; (2S,4R,5S)-(4-Hydroxy-5-methyltetrahydrofuran-2-yl)methyl-trimethylammonium chloride
EINECS	218-966-5

Quality Control

Our (+)-Muscarine Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade standards. For specific purity requirements or custom analytical protocols, please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.