Description

2-Chloro-5-Fluorobenzoic Acid is a versatile fluorinated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of halogen substituents, which enable selective functionalization and the construction of complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated aromatic systems.
• Agrochemical Synthesis: Building block for manufacturing herbicides, fungicides, and insecticides that benefit from halogenated aromatic cores.
• Liquid Crystal & OLED Materials: Used in the production of fluorinated components for electronic display and lighting technologies.
• Organic Synthesis & Research: Versatile reagent for Suzuki-Miyaura and other cross-coupling reactions to create biaryl structures.
• Polymer Modification: Intermediate for introducing fluorinated benzoic acid groups into polymers to alter physical properties.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in chemical production.

Basic Information

Product Name	2-Chloro-5-Fluorobenzoic Acid
CAS No.	2252-50-8
Molecular Formula	C7H4ClFO2
Molecular Weight	174.56 g/mol
Synonyms	5-Fluoro-2-chlorobenzoic Acid; 2-Chloro-5-fluorobenzoic Acid; Benzoic acid, 2-chloro-5-fluoro-; 2-Chloro-5-fluorobenzenecarboxylic Acid; 2252-50-8; 5-Fluoro-o-chlorobenzoic Acid; NSC 403119; 2-Chloro-5-fluoro-benzoic acid
EINECS	218-848-3

Quality Control

Our 2-Chloro-5-Fluorobenzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	155°C - 160°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.