Description

2-Bromo-6-Fluorobenzoic Acid is a versatile halogenated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This high-purity intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromo-fluoro aromatic motifs into their target compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the bromine and fluorine atoms contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers with tailored electronic properties.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Bromo-6-Fluorobenzoic Acid
CAS No.	2252-37-1
Molecular Formula	C7H4BrFO2
Molecular Weight	219.01 g/mol
Synonyms	6-Fluoro-2-bromobenzoic Acid; 2-Bromo-6-fluorobenzoic acid; Benzoic acid, 2-bromo-6-fluoro-; o-Bromo-o-fluorobenzoic Acid; 2-Bromo-6-fluorobenzenecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Fluorobenzoic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.