Description

4-Fluoro-A-Oxo-Benzeneacetic Acid is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. This compound serves as a key intermediate for the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of fluorine atoms is a critical strategy for modulating biological activity and metabolic stability. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of fluorinated drug candidates, including potential anti-inflammatory and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the fluorine moiety enhances efficacy and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in displays and lighting.
• Advanced Polymer Modification: Employed to introduce fluorinated side chains into polymers, altering surface properties, chemical resistance, and thermal stability.
• Organic Synthesis Reagent: Acts as a versatile reagent in cross-coupling reactions and for the preparation of other fluorinated fine chemicals and ligands.

Basic Information

Product Name	4-Fluoro-A-Oxo-Benzeneacetic Acid
CAS No.	2251-76-5
Molecular Formula	C8H5FO3
Molecular Weight	168.12 g/mol
Synonyms	4-Fluorobenzoylformic Acid; 4-Fluorophenylglyoxylic Acid; 2-Oxo-2-(4-fluorophenyl)acetic Acid; 4-Fluorobenzoyl Formic Acid; p-Fluorobenzoylformic Acid; α-Oxo-4-fluorobenzeneacetic Acid; (4-Fluorophenyl)(oxo)acetic Acid
EINECS	Contact for details

Quality Control

Our 4-Fluoro-A-Oxo-Benzeneacetic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.