Description

5-Fluoro-1-[(2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-4-Methy Lamino-Pyrimidin-2-One is a high-purity nucleoside analog intermediate of significant commercial and research importance. Its precise stereochemistry and functional groups make it a critical building block for the synthesis of advanced pharmaceutical compounds. This product is essential for manufacturers and research institutions in the pharmaceutical and biotechnology sectors, particularly those developing antiviral and anticancer therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside-based antiviral and anticancer drugs.
• Antiviral Drug Development: Used in research and production of compounds targeting viral polymerases and reverse transcriptases.
• Oncology Research: Serves as a building block for creating chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to investigate metabolic pathways.
• Process Chemistry: Utilized in scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals.

Basic Information

Item	Details
Product Name	5-Fluoro-1-[(2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-4-Methy Lamino-Pyrimidin-2-One
CAS No.	2248-73-9
Molecular Formula	C11H15FN3O5
Molecular Weight	288.25 g/mol
Synonyms	5-Fluoro-1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-4-(methylamino)pyrimidin-2(1H)-one; 5-Fluoro-N4-methyl-2'-deoxycytidine; 5-Fluoro-2'-deoxy-N4-methylcytidine; Fd4M; 5-Fluoro-2'-deoxy-4-methylaminocytidine; 5-Fluoro-4-methylamino-2'-deoxycytidine; 5-F-d4M; 2248-73-9
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1-[(2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-4-Methy Lamino-Pyrimidin-2-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0%
Purity (HPLC, Area%)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.