Description

Didesipramine CAS NO 2095-95-6 is a high-purity chemical compound belonging to the tricyclic antidepressant class, specifically a tertiary amine derivative. This compound is of significant interest in pharmaceutical research and development for its role as a key intermediate or reference standard. It is primarily required by research institutions, pharmaceutical manufacturers, and analytical laboratories engaged in neuropharmacology studies, method development, and quality control processes.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of more complex tricyclic antidepressant agents and related pharmacologically active molecules.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method validation, calibration, and ensuring the accuracy of assay results in drug testing.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate the mechanisms of action, metabolism, and structure-activity relationships (SAR) of tricyclic compounds.
• Active Pharmaceutical Ingredient (API) Development: Utilized in the research phase for formulating new drug candidates targeting neurological disorders.
• Quality Control & Assurance: Acts as a benchmark for identifying and quantifying impurities in bulk drug substances and finished dosage forms within pharmaceutical manufacturing.

Basic Information

Product Name	Didesipramine
CAS No.	2095-95-6
Molecular Formula	C19H24N2
Molecular Weight	280.41 g/mol
Synonyms	Desipramine Impurity C; Didesmethylimipramine; Norimipramine; NSC 75726; 10,11-Dihydro-5-[3-(methylamino)propyl]-5H-dibenz[b,f]azepine; 3-(10,11-Dihydro-5H-dibenz[b,f]azepin-5-yl)-N-methylpropan-1-amine; Didesmethylimipramine Hydrochloride (salt form)
EINECS	Contact for details

Quality Control

Our Didesipramine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity determination by HPLC, and control of specified impurities. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.