Description

2-Hydroxy Trimipramine is a key pharmaceutical intermediate and metabolite of the tricyclic antidepressant trimipramine. This compound matters for its critical role in drug metabolism studies, pharmacokinetic research, and the development of analytical reference standards. It is primarily needed by pharmaceutical R&D laboratories, analytical testing facilities, and manufacturers of active pharmaceutical ingredients (APIs) and high-purity fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis and research of tricyclic antidepressant compounds.
• Metabolite Reference Standard: Used as an analytical standard in bioanalytical methods for studying the metabolism and pharmacokinetics of trimipramine.
• Biochemical Research: Employed in in-vitro and in-vivo studies to understand the pharmacological activity and metabolic pathways of related therapeutics.
• Quality Control & Assurance: Essential for the development and validation of HPLC, LC-MS, and other chromatographic methods in pharmaceutical quality control laboratories.
• Academic Research: Utilized in universities and research institutions for neuropharmacology and medicinal chemistry projects.

Basic Information

Product Name	2-Hydroxy Trimipramine
CAS No.	2064-15-5
Molecular Formula	C20H26N2O
Molecular Weight	310.44 g/mol
Synonyms	2-Hydroxytrimipramine; 10,11-Dihydro-N,N,β-trimethyl-5H-dibenzo[b,f]azepine-5-propanamine, 2-hydroxy-; 5-(3-Dimethylaminopropyl)-10,11-dihydro-2-hydroxy-5H-dibenzo[b,f]azepine; Trimipramine metabolite 2-OH; 2-OH-Trimipramine
EINECS	Contact for details

Quality Control

Our 2-Hydroxy Trimipramine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identity confirmation by IR and NMR, purity assessment by HPLC, and control of specified impurities. A Certificate of Analysis (COA) detailing all test results is provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and in original packaging until use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.