Description

Ganciclovir Sodium is the sodium salt form of the potent antiviral nucleoside analogue ganciclovir. This compound is a critical active pharmaceutical ingredient (API) used in the formulation of injectable antiviral medications. It is primarily required by pharmaceutical manufacturers and research institutions developing treatments for severe cytomegalovirus (CMV) infections. The product is supplied as a high-purity material suitable for pharmaceutical synthesis and advanced research applications.

Application

• Primary Active Pharmaceutical Ingredient (API) in injectable antiviral formulations.
• Manufacturing of lyophilized powder for injection to treat cytomegalovirus (CMV) retinitis in immunocompromised patients.
• Research and development of novel antiviral therapies and drug delivery systems.
• Production of ophthalmic gels for the treatment of herpetic keratitis (under investigation).
• Reference standard in analytical laboratories for quality control and method development.
• Biochemical research involving the study of viral DNA polymerase inhibition mechanisms.

Basic Information

Product Name	Ganciclovir Sodium
CAS No.	299-61-6
Molecular Formula	C9H12N5NaO4
Molecular Weight	277.21 g/mol
Synonyms	9-[(1,3-Dihydroxy-2-propoxy)methyl]guanine Sodium Salt; Ganciclovir Sodium Salt; DHPG Sodium Salt; Cytovene Sodium; Cymevene Sodium; Sodium 2-Amino-1,9-dihydro-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6H-purin-6-one; BMY-39561 Sodium Salt
EINECS	Contact for details

Quality Control

Our Ganciclovir Sodium is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical applications, with typical purity exceeding 98.5% (by HPLC). A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for assay, related substances, residual solvents, and microbiological limits. We can support compliance with ICH Q7 guidelines and relevant pharmacopeial standards (USP/EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.5% - 101.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Bacterial Endotoxins	< 0.5 EU/mg
Microbial Limit	Complies with USP <61> and <62>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.