Description

3-Bromo-2-Fluoro-5-Iodo-Benzoic Acid is a high-purity, multi-halogenated benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it an invaluable intermediate for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists working on new active ingredients, where its structure enables precise molecular modifications.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in oncology and CNS drug discovery.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides requiring halogenated aromatic cores.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Building block for creating functionalized polymers and organic electronic materials with specific halogen-based properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological systems and mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects and scale-up activities.

Basic Information

Product Name	3-Bromo-2-Fluoro-5-Iodo-Benzoic Acid
CAS No.	1992023-57-0
Molecular Formula	C7H3BrFIO2
Molecular Weight	344.90 g/mol
Synonyms	3-Bromo-2-fluoro-5-iodobenzoic acid; Benzoic acid, 3-bromo-2-fluoro-5-iodo-; 2-Fluoro-3-bromo-5-iodobenzoic acid; 5-Iodo-3-bromo-2-fluorobenzoic acid; AI3-72442; BRN 9086405; ZINC000257070587; SCHEMBL21824027
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Fluoro-5-Iodo-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP standards for advanced intermediate production, ensuring traceability and consistency for critical R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.