Description

3-(Difluoromethyl)Isoxazole-5-Carboxylic Acid (Wxfc0767) is a high-purity, heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. Its unique structure, featuring a difluoromethyl-substituted isoxazole core, makes it a critical intermediate for the development of novel active compounds. This product is primarily utilized by pharmaceutical and agrochemical research organizations seeking to incorporate fluorinated heterocycles into their molecular libraries. We supply this material with a focus on batch-to-batch consistency and reliable global delivery to support your R&D and scale-up projects.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting fluorinated drug candidates.
• Agrochemical Synthesis: Serves as a versatile building block for creating novel herbicides, fungicides, and insecticides, where the difluoromethyl group can enhance biological activity and metabolic stability.
• Chemical Biology & Proteomics: Used in the design and synthesis of chemical probes, enzyme inhibitors, and molecular tags for studying biological systems.
• Material Science Research: Employed as a monomer or functional component in the development of advanced polymers and specialty materials with tailored properties.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	3-(Difluoromethyl)Isoxazole-5-Carboxylic Acid (Wxfc0767)
CAS No.	1935503-24-4
Molecular Formula	C6H3F2NO3
Molecular Weight	175.09 g/mol
Synonyms	3-(Difluoromethyl)-1,2-oxazole-5-carboxylic acid; 5-Isoxazolecarboxylic acid, 3-(difluoromethyl)-; WX-FC0767; Wxfc0767; 3-Difluoromethylisoxazole-5-carboxylic acid; 3-(Difluoromethyl)-5-carboxyisoxazole; DFMIA; Difluoromethylisoxazole carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 3-(Difluoromethyl)Isoxazole-5-Carboxylic Acid is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.