Description

Remdesivir-001-Lr is a high-purity pharmaceutical intermediate and reference standard, identified by CAS No. 1911578-99-8. This compound is critical for ensuring the quality, safety, and efficacy of antiviral drug development and manufacturing processes. It is primarily required by pharmaceutical companies, contract research organizations (CROs), and analytical laboratories engaged in the synthesis and quality control of antiviral therapeutics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of Remdesivir and related antiviral prodrugs.
• Reference Standard: Used for analytical method development, validation, and quality control (QC) testing in compliance with pharmacopeial guidelines.
• Research & Development: Serves as a crucial material in preclinical and clinical research for studying antiviral mechanisms and efficacy.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the controlled synthesis of the final active drug substance under cGMP conditions.
• Impurity Profiling: Utilized as a marker to identify, quantify, and control related substances and degradation products in drug formulations.

Basic Information

Product Name	Remdesivir-001-Lr
CAS No.	1911578-99-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	GS-5734 Impurity; Remdesivir Related Compound; (2R,3S,4R,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile; Veklury Intermediate; Remdesivir-Lr; 1911578-99-8; GS-441524 Impurity
EINECS	Contact for details

Quality Control

Our Remdesivir-001-Lr is manufactured and tested under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific pharmacopeial (e.g., USP, EP) or client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.