Description

(1R,2S)-2-Amino-3-Methyl-1-Phenylbutan-1-Ol is a chiral amino alcohol building block of significant importance in asymmetric synthesis. This compound matters because it serves as a key intermediate for the production of high-value pharmaceuticals, including antiviral and cardiovascular drugs, where its defined stereochemistry is critical for biological activity. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral and central nervous system (CNS) drug candidates.
• Asymmetric Catalyst Ligand: Used as a precursor or direct ligand in the development of chiral catalysts for enantioselective hydrogenation and other catalytic transformations.
• Agrochemical Synthesis: Employed in the research and production of advanced, stereochemically-defined pesticides and herbicides.
• Fine Chemical Building Block: Serves as a versatile starting material for constructing complex natural products and specialty chemicals in organic chemistry R&D.
• Academic & Industrial Research: A valuable reagent for methodological studies in organic synthesis and medicinal chemistry within university and corporate R&D laboratories.

Basic Information

Product Name	(1R,2S)-2-Amino-3-Methyl-1-Phenylbutan-1-Ol
CAS No.	1893415-26-3
Molecular Formula	C11H17NO
Molecular Weight	179.26 g/mol
Synonyms	(1R,2S)-2-Amino-3-methyl-1-phenyl-1-butanol; (1R,2S)-1-Phenyl-2-amino-3-methylbutan-1-ol; L-threo-2-Amino-1-phenyl-1-butanol; (1R,2S)-APB; Amino alcohol CAS 1893415-26-3; Chiral amino alcohol intermediate; Phenyl amino butanol derivative
EINECS	Contact for details

Quality Control

Our (1R,2S)-2-Amino-3-Methyl-1-Phenylbutan-1-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure compliance with high-purity standards suitable for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.