Description

(2R,2'R,3R,3'R)-3,3'-Di-tert-Butyl-4,4'-Bis(2,6-Dimethoxyphenyl)-2,2',3,3'-Tetrahydro-2,2'-Bibenzo[D][1,3]Oxaphosphole CAS NO 1884680-48-1 is a high-purity, chiral organophosphorus compound characterized by its unique binaphthyl-oxaphosphole backbone. This compound is valued for its role as a sophisticated ligand or catalyst precursor in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric reactions, including hydrogenation, cross-coupling, and C-H activation.
• As a key intermediate or catalyst precursor in the synthesis of active pharmaceutical ingredients (APIs) requiring high enantiomeric excess.
• In asymmetric organocatalysis for the construction of complex molecular architectures.
• For academic and industrial R&D in developing new catalytic methodologies and chiral materials.
• Potential use in the synthesis of advanced electronic materials and liquid crystals where chirality influences properties.

Basic Information

Product Name	(2R,2'R,3R,3'R)-3,3'-Di-tert-Butyl-4,4'-Bis(2,6-Dimethoxyphenyl)-2,2',3,3'-Tetrahydro-2,2'-Bibenzo[D][1,3]Oxaphosphole
CAS No.	1884680-48-1
Molecular Formula	C44H48O6P2
Molecular Weight	734.78 g/mol
Synonyms	(R,R,R,R)-3,3'-Di-tert-butyl-4,4'-bis(2,6-dimethoxyphenyl)-2,2',3,3'-tetrahydro-2,2'-bibenzo[d][1,3]oxaphosphole; DTBP-BINAP-Oxaphosphole Derivative; Chiral Binaphthyl Oxaphosphole Ligand; (2R,2'R,3R,3'R)-DTB-Bis(DMP)-H8-BINAP-O; P-OP Bidentate Ligand; (all-R)-Enantiomer; 1884680-48-1; CAS 1884680-48-1
EINECS	Contact for details

Quality Control

Every batch of our (2R,2'R,3R,3'R)-3,3'-Di-tert-Butyl-4,4'-Bis(2,6-Dimethoxyphenyl)-2,2',3,3'-Tetrahydro-2,2'-Bibenzo[D][1,3]Oxaphosphole is manufactured under strict quality management systems. We guarantee high chiral purity and chemical integrity, with specifications tailored to meet the rigorous demands of asymmetric synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), enantiomeric excess, and impurity profiles is provided with each shipment to ensure full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Keep the container sealed in a desiccator to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.