Description

1-Palmitoyl-D9-2-Palmitoyl-Sn-Glycerol is a deuterated isotopologue of a key diacylglycerol (DAG) lipid, specifically designed for use as an internal standard in quantitative mass spectrometry. This compound is critical for ensuring analytical accuracy and reproducibility in lipidomic research, where precise quantification is paramount. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, biotechnology, and nutritional science sectors who require high-fidelity standards for metabolic pathway analysis and biomarker discovery.

Application

• Quantitative Lipidomics: Serves as a stable isotope-labeled internal standard for the absolute quantification of endogenous diacylglycerols (DAGs) in biological samples via LC-MS/MS.
• Metabolic Research: Used in tracer studies to investigate lipid metabolism, signaling pathways, and the role of DAGs in cellular processes like insulin resistance and energy homeostasis.
• Pharmaceutical Development: Enables precise pharmacokinetic and pharmacodynamic studies of lipid-based drug formulations and metabolic modulators.
• Clinical Diagnostics: Supports the development and validation of diagnostic assays for metabolic disorders by providing a reliable reference compound.
• Biomarker Discovery: Facilitates the accurate measurement of DAG species in plasma, tissues, or cell cultures to identify and validate disease biomarkers.
• Food & Nutritional Science: Applied in research to analyze lipid composition and metabolism in nutritional studies and functional food development.

Basic Information

Product Name	1-Palmitoyl-D9-2-Palmitoyl-Sn-Glycerol
CAS No.	1872379-48-0
Molecular Formula	C35H58D9O5
Molecular Weight	~ 588.0 g/mol
Synonyms	1,2-Dipalmitoyl-D9-sn-glycerol; D9-Dipalmitoylglycerol; Deuterated DAG (16:0/16:0); 1-Palmitoyl(d9)-2-palmitoyl-rac-glycerol; (2R)-2,3-Bis(palmitoyloxy)propyl 1,1,2,3,3,4,4,5,5-nonadeuteriopentadecanoate; sn-1-Palmitoyl(d9)-sn-2-palmitoylglycerol; DPPG-d9; Lipid Internal Standard DAG-d9
EINECS	Contact for details

Quality Control

Our 1-Palmitoyl-D9-2-Palmitoyl-Sn-Glycerol is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and solvent content. We adhere to relevant industry standards for high-purity reference materials to guarantee reliable and reproducible performance in your sensitive analytical methods.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and ensure long-term stability. Allow the vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.