Description

Velpatasvir Co Povidone is a pharmaceutical-grade co-processed excipient specifically designed for use in the formulation of solid dosage forms. This material is critical for enhancing the solubility and bioavailability of the active pharmaceutical ingredient (API) Velpatasvir, a key component in antiviral therapies. It is an essential raw material for pharmaceutical manufacturers and R&D facilities developing and producing high-quality, effective antiviral medications.

Application

• Primary excipient in the formulation of Velpatasvir-based solid oral dosage forms (e.g., tablets, capsules).
• Used to improve the dissolution rate and bioavailability of poorly soluble APIs through amorphization and stabilization.
• Critical component in the manufacture of fixed-dose combination (FDC) products for the treatment of Hepatitis C Virus (HCV).
• Employed in pharmaceutical research and development for pre-formulation and formulation optimization studies.
• Applicable in hot-melt extrusion (HME) and spray-drying processes to create stable amorphous solid dispersions.
• Serves as a carrier and stabilizer in advanced drug delivery systems to ensure consistent drug performance.

Basic Information

Product Name	Velpatasvir Co Povidone
CAS No.	1844064-96-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Velpatasvir and Povidone Co-Processed Excipient; Velpatasvir-PVP VA64 Solid Dispersion; Copovidone-Velpatasvir Mixture; Amorphous Velpatasvir Solid Dispersion Carrier; PVP-VA 64 with Velpatasvir; Pharmaceutical Excipient for Velpatasvir; HCV Drug Formulation Excipient
EINECS	Contact for details

Quality Control

Our Velpatasvir Co Povidone is manufactured under strict quality systems suitable for pharmaceutical applications. Each batch is tested to ensure it meets stringent specifications for identity, purity, and performance. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for assay, related substances, residual solvents, and key physicochemical properties. Our quality commitment aligns with cGMP principles and relevant ICH guidelines to support global regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a low-humidity environment to prevent absorption of water, which may affect performance. The container should be kept sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white amorphous solid
Identification (IR)	Conforms
Assay (Velpatasvir Content)	Contact for details
Related Substances (HPLC)	NMT specified limits
Water Content (KF)	NMT 5.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	Complies with USP/ICH guidelines
Dissolution Performance	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.