Description

Methyl 2-Fluoro-3-Iodo-6-(Methylsulfonyl)Benzoate is a high-value, multi-functionalized aromatic building block designed for advanced synthetic chemistry. This compound matters for its unique combination of halogen and sulfonyl substituents, which are critical for modulating the electronic and steric properties of target molecules in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for constructing complex heterocycles and as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic materials.
• Cross-Coupling Reactions: The iodine and fluorine atoms make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Ligand Synthesis: Utilized in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Acts as a starting material for synthesizing fluorescent tags or molecular probes for biochemical assays.

Basic Information

Product Name	Methyl 2-Fluoro-3-Iodo-6-(Methylsulfonyl)Benzoate
CAS No.	1823565-96-3
Molecular Formula	C9H8FIO4S
Molecular Weight	358.12 g/mol
Synonyms	Methyl 2-Fluoro-3-iodo-6-(methylsulfonyl)benzoate; Benzoic acid, 2-fluoro-3-iodo-6-(methylsulfonyl)-, methyl ester; 2-Fluoro-3-iodo-6-(methylsulfonyl)benzoic acid methyl ester; Methyl 2-fluoro-3-iodo-6-methanesulfonylbenzoate; 1823565-96-3; Methyl 2-Fluoro-3-Iodo-6-(Methylsulfonyl)Benzoate CAS 1823565-96-3
EINECS	Contact for details

Quality Control

Our Methyl 2-Fluoro-3-Iodo-6-(Methylsulfonyl)Benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency essential for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to light and potential for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.