Description

Methyl 2-Amino-4-Fluoro-5-Iodobenzoate CAS NO 1823565-63-4 is a high-purity, multi-functional halogenated benzoate derivative, serving as a critical advanced pharmaceutical intermediate. Its molecular structure, featuring strategically placed amino, fluoro, and iodo substituents, makes it a versatile building block for constructing complex bioactive molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for synthesizing novel drug candidates and active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated aromatic core.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals due to its electron-deficient aromatic system.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom chemical synthesis and scale-up projects under cGMP or ISO standards.
• Academic & Industrial R&D: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	Methyl 2-Amino-4-Fluoro-5-Iodobenzoate
CAS No.	1823565-63-4
Molecular Formula	C8H7FINO2
Molecular Weight	295.05 g/mol
Synonyms	2-Amino-4-fluoro-5-iodobenzoic acid methyl ester; Methyl 2-amino-4-fluoro-5-iodobenzoate; Benzoic acid, 2-amino-4-fluoro-5-iodo-, methyl ester; 4-Fluoro-5-iodoanthranilic acid methyl ester; Methyl 4-fluoro-5-iodoanthranilate
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-Amino-4-Fluoro-5-Iodobenzoate is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.