Description

3-Pyrrolidinecarboxylic Acid, 4-Phenyl-1-(Phenylmethyl)-, (3S,4R)- is a chiral, non-natural amino acid derivative featuring a pyrrolidine scaffold substituted with phenyl and benzyl groups. This compound matters as a sophisticated and versatile chiral building block, enabling the synthesis of complex molecules with precise stereochemistry. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, asymmetric synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in protease inhibitor and CNS-targeted therapies.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts.
• Peptidomimetics & Constrained Peptide Design: Used to introduce conformational rigidity and specific stereocenters into peptide backbones for enhanced biological activity and stability.
• Agrochemical Research: Employed in the synthesis of advanced, stereochemically-defined active ingredients for crop protection.
• Chemical Biology Probes: Useful for creating labeled or modified probes to study enzyme mechanisms and protein-ligand interactions.
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists exploring new methodologies and complex molecular architectures.

Basic Information

Product Name	3-Pyrrolidinecarboxylic Acid, 4-Phenyl-1-(Phenylmethyl)-, (3S,4R)-
CAS No.	1821739-17-6
Molecular Formula	C18H19NO2
Molecular Weight	281.35 g/mol
Synonyms	(3S,4R)-4-Phenyl-1-benzylpyrrolidine-3-carboxylic Acid; (3S,4R)-1-Benzyl-4-phenylpyrrolidine-3-carboxylic Acid; 1-Benzyl-4-phenyl-L-proline; (3S,4R)-1-Benzyl-4-phenyl-3-pyrrolidinecarboxylic Acid; 4-Phenyl-1-(phenylmethyl)-(3S,4R)-3-pyrrolidinecarboxylic Acid; (3S,4R)-1-Benzyl-4-phenylproline; (3S,4R)-1-Bn-4-Ph-Pyrrolidine-3-COOH
EINECS	Contact for details

Quality Control

Our 3-Pyrrolidinecarboxylic Acid, 4-Phenyl-1-(Phenylmethyl)-, (3S,4R)- is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.