Description

(1S)-3-[[(9S)-Cinchonan-9-Ylimino]Methyl]-2’-[[(tert-Butyl)Diphenylsilyl]Oxy]-[1,1’-Binaphthalen]-2-Ol is a sophisticated chiral organosilicon compound derived from cinchona alkaloid and binaphthol frameworks. This advanced intermediate is critical for its role in asymmetric synthesis, particularly as a precursor or ligand for high-value catalytic transformations. It is essential for research and development chemists in the pharmaceutical and fine chemical sectors who require high-purity, structurally complex building blocks to develop novel active pharmaceutical ingredients (APIs) and specialty materials.

Application

• As a key chiral ligand or precursor in the development of asymmetric catalysts for organic synthesis.
• As an advanced synthetic intermediate in the research and production of novel pharmaceuticals and bioactive molecules.
• For use in methodology development within academic and industrial R&D laboratories focusing on stereoselective reactions.
• In the synthesis of specialty fine chemicals where precise control over molecular chirality is paramount.
• Potential application in the preparation of functional materials with specific optical or electronic properties.

Basic Information

Product Name	(1S)-3-[[(9S)-Cinchonan-9-Ylimino]Methyl]-2’-[[(tert-Butyl)Diphenylsilyl]Oxy]-[1,1’-Binaphthalen]-2-Ol
CAS No.	1809433-24-6
Molecular Formula	C₅₅H₅₄N₂O₂Si
Molecular Weight	803.13 g/mol
Synonyms	(S)-3-(((9S)-Cinchonan-9-ylimino)methyl)-2'-((tert-butyldiphenylsilyl)oxy)-[1,1'-binaphthalen]-2-ol; (S)-TBDPS-protected Cinchona-BINOL Hybrid Ligand; Cinchona-BINOL-TBDPS Derivative; (1S,9S)-Cinchona-Binaphthol Silyl Ether; Asymmetric Catalyst Intermediate; Chiral Binaphthyl-Cinchona Alkaloid Conjugate; TBDPS-O-Cinchona-BINOL; 1809433-24-6
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing specifications such as HPLC purity, chiral purity, and NMR confirmation are available upon request. We adhere to strict quality management protocols suitable for R&D and pre-clinical pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.