Description

2-Fluoro-4-Iodo-5-Nitro-Benzoic Acid Methyl Ester is a high-purity, multi-functional aromatic building block designed for advanced synthetic chemistry. This compound is valued for its unique halogenated and nitrated structure, which provides distinct reactivity for constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications such as medicinal chemistry, ligand synthesis, and the development of functional organic compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting various disease pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a precursor for organic electronic materials, liquid crystals, and photoactive polymers.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and for introducing fluorine and iodine atoms to modulate the pharmacokinetic properties of drug candidates.
• Chemical Biology: Useful as a probe or labeling reagent due to the presence of the iodine atom, which can be used for further functionalization or tracking.
• Academic & Industrial R&D: A versatile reagent for methodological development in organic synthesis, including cross-coupling reactions and nucleophilic aromatic substitution.

Basic Information

Product Name	2-Fluoro-4-Iodo-5-Nitro-Benzoic Acid Methyl Ester
CAS No.	1807741-24-7
Molecular Formula	C9H5FINO4
Molecular Weight	321.04 g/mol
Synonyms	Methyl 2-Fluoro-4-Iodo-5-Nitrobenzoate; Benzoic acid, 2-fluoro-4-iodo-5-nitro-, methyl ester; 2-Fluoro-4-iodo-5-nitrobenzoic acid methyl ester; Methyl 2-fluoro-4-iodo-5-nitrobenzoate; 1807741-24-7; 5-Nitro-2-fluoro-4-iodobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-Iodo-5-Nitro-Benzoic Acid Methyl Ester is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for research and fine chemical intermediates. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to verify identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.