Description

5-Chloro-2-Fluoro-3-(Trifluoromethyl)Benzoic Acid is a high-value, multi-functional aromatic carboxylic acid building block distinguished by its unique halogenated and trifluoromethylated structure. This compound is critical for introducing specific steric and electronic properties into target molecules, enabling the development of advanced materials and active ingredients. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for advanced electronic materials, contributing to the molecular design of liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart specific chemical resistance, thermal stability, or surface properties.
• Organic Synthesis & Catalysis: Acts as a versatile reagent in cross-coupling reactions and as a ligand precursor in organometallic catalysis.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	5-Chloro-2-Fluoro-3-(Trifluoromethyl)Benzoic Acid
CAS No.	1807119-60-3
Molecular Formula	C8H3ClF4O2
Molecular Weight	242.56 g/mol
Synonyms	5-Chloro-2-fluoro-3-(trifluoromethyl)benzoic acid; 2-Fluoro-5-chloro-3-(trifluoromethyl)benzoic acid; 3-(Trifluoromethyl)-5-chloro-2-fluorobenzoic acid; Benzoic acid, 5-chloro-2-fluoro-3-(trifluoromethyl)-; 1807119-60-3; 5-Chloro-2-fluoro-alpha,alpha,α-trifluoro-m-toluic acid
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Fluoro-3-(Trifluoromethyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.