Description

2,3-Difluoro-4-Nitro-Benzoic Acid is a high-purity, multi-functional aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both electron-withdrawing nitro and carboxylic acid groups on a difluorinated benzene ring, makes it a versatile precursor for creating complex molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients, particularly in the development of fluorinated drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), leveraging fluorine's ability to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the difluoro-nitro-benzoic acid scaffold contributes to enhanced activity and environmental profile.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a scaffold for designing enzyme inhibitors, activity-based probes, and other biochemical tools due to its reactive handles for conjugation.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2,3-Difluoro-4-Nitro-Benzoic Acid
CAS No.	1806370-35-3
Molecular Formula	C7H3F2NO4
Molecular Weight	203.10 g/mol
Synonyms	4-Nitro-2,3-difluorobenzoic Acid; 2,3-Difluoro-4-nitrobenzoic Acid; Benzoic acid, 2,3-difluoro-4-nitro-; 1806370-35-3; 2,3-Difluoro-4-nitro-benzoic acid; 2,3-Difluoro-4-nitrobenzoic acid; 4-Nitro-2,3-difluorobenzoic acid
EINECS	Contact for details

Quality Control

Every batch of 2,3-Difluoro-4-Nitro-Benzoic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We provide Certificates of Analysis (COA) that detail purity, identity, and impurity profiles, ensuring traceability and compliance with your research or production requirements. Our quality commitment supports applications demanding high standards, including cGMP (current Good Manufacturing Practice) for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and reducing agents. Recommended storage temperature is between 15°C and 25°C. The compound is compatible with standard laboratory and industrial storage conditions for solid organic acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.