Description

Methyl 2-Bromo-4-Cyano-3-Fluorobenzoate is a high-purity, multi-functional aromatic ester building block designed for advanced synthetic chemistry. This compound is valued for its unique combination of reactive halogen, nitrile, and fluorine substituents, enabling precise molecular construction in complex chemical synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for constructing specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of functionalized monomers for advanced polymers and liquid crystals.
• Chemical Biology Probes: Acts as a building block for synthesizing fluorescent tags and molecular probes for biochemical assays.
• Custom Synthesis and Scale-Up: An essential starting material for contract research and manufacturing organizations (CROs/CMOs) performing custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	Methyl 2-Bromo-4-Cyano-3-Fluorobenzoate
CAS No.	1805523-50-5
Molecular Formula	C9H5BrFNO2
Molecular Weight	258.05 g/mol
Synonyms	2-Bromo-4-cyano-3-fluorobenzoic acid methyl ester; Methyl 2-bromo-4-cyano-3-fluorobenzoate; Benzoic acid, 2-bromo-4-cyano-3-fluoro-, methyl ester; 3-Fluoro-2-bromo-4-cyanobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Bromo-4-Cyano-3-Fluorobenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.