Description

Benzoic Acid, 6-Chloro-2-Fluoro-3-(Trifluoromethyl)-, Methyl Ester is a high-value, multi-functional fluorinated aromatic building block. This compound is engineered to introduce a unique combination of halogen and trifluoromethyl substituents into advanced molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. Its specific substitution pattern makes it a critical intermediate for creating compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups improve efficacy and environmental profile.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials requiring specific fluorinated aromatic units.
• Chemical Biology & Proteomics: Employed as a tagging or labeling reagent in the development of chemical probes for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	Benzoic Acid, 6-Chloro-2-Fluoro-3-(Trifluoromethyl)-, Methyl Ester
CAS No.	1805458-07-4
Molecular Formula	C10H5ClF4O2
Molecular Weight	268.59 g/mol
Synonyms	Methyl 6-Chloro-2-fluoro-3-(trifluoromethyl)benzoate; 6-Chloro-2-fluoro-3-(trifluoromethyl)benzoic Acid Methyl Ester; 2-Fluoro-6-chloro-α,α,α-trifluoro-m-toluic Acid Methyl Ester; Benzoic acid, 6-chloro-2-fluoro-3-(trifluoromethyl)-, methyl ester; Methyl 2-fluoro-6-chloro-3-(trifluoromethyl)benzoate
EINECS	Contact for details

Quality Control

Every batch of our Benzoic Acid, 6-Chloro-2-Fluoro-3-(Trifluoromethyl)-, Methyl Ester is produced and analyzed under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the exacting standards required for research and process development. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC), identity confirmation (by NMR and IR), and impurity profiles. Our quality commitment supports compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.