Description

2-Amino-5-Bromo-3-Trifluoromethyl-Benzoic Acid Methyl Ester is a high-purity, multi-functional chemical intermediate designed for advanced synthesis. This compound matters for its unique trifluoromethyl and bromo substituents, which are critical for modulating the physicochemical and biological properties of target molecules. It is primarily needed by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex molecules for drug discovery, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced activity.
• Material Science Research: Serves as a precursor for specialty polymers and advanced organic electronic materials due to its halogenated and fluorinated aromatic structure.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke chemical synthesis projects.

Basic Information

Product Name	2-Amino-5-Bromo-3-Trifluoromethyl-Benzoic Acid Methyl Ester
CAS No.	1805449-93-7
Molecular Formula	C9H6BrF3NO2
Molecular Weight	298.05 g/mol
Synonyms	Methyl 2-Amino-5-Bromo-3-(trifluoromethyl)benzoate; 2-Amino-5-bromo-α,α,α-trifluoro-m-toluic acid methyl ester; Benzoic acid, 2-amino-5-bromo-3-(trifluoromethyl)-, methyl ester; 1805449-93-7; Methyl 2-amino-5-bromo-α,α,α-trifluoro-m-toluate
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Bromo-3-Trifluoromethyl-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high standards, including cGMP-compliant synthesis for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.