Description

3-Bromo-2-Chloro-5-Fluorobenzoic Acid is a high-purity, multi-halogenated benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it an invaluable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the halogen atoms contribute to bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of advanced organic electronic materials, such as semiconductors and liquid crystals, due to its electron-withdrawing halogen groups.
• Custom Synthesis and Contract Manufacturing: A vital substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Item	Details
Product Name	3-Bromo-2-Chloro-5-Fluorobenzoic Acid
CAS No.	1805210-37-0
Molecular Formula	C7H3BrClFO2
Molecular Weight	253.45 g/mol
Synonyms	3-Bromo-2-chloro-5-fluorobenzoic acid; 2-Chloro-3-bromo-5-fluorobenzoic acid; 5-Fluoro-3-bromo-2-chlorobenzoic acid; Benzoic acid, 3-bromo-2-chloro-5-fluoro-; 1805210-37-0; BCFBA (abbreviation); 3-Br-2-Cl-5-F-BA
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2-Chloro-5-Fluorobenzoic Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure reliable purity and batch-to-batch consistency, which is critical for your synthetic processes. A detailed Certificate of Analysis (COA) specifying identity, purity (typically ≥97% by HPLC), and impurity profiles is supplied with each shipment. Our quality protocols are designed to meet the stringent requirements of GMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.