Description

2-Bromo-5-Fluoro-4-Nitro-Benzoic Acid is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. Its unique halogenated and nitro-substituted benzoic acid structure makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing active ingredients and novel functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogen and nitro functional groups for bioactivity.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the fluorine and bromine atoms enhance biological activity and environmental stability.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials due to its aromatic core and electron-withdrawing substituents.
• Chemical Biology & Proteomics: Employed in the design and synthesis of chemical probes, enzyme inhibitors, and linker molecules for bioconjugation and target identification studies.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing complex, color-fast dyes and organic pigments, leveraging the nitro group as a chromophore.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated benzoic acid derivatives.

Basic Information

Product Name	2-Bromo-5-Fluoro-4-Nitro-Benzoic Acid
CAS No.	1805189-72-3
Molecular Formula	C7H3BrFNO4
Molecular Weight	264.01 g/mol
Synonyms	4-Nitro-2-bromo-5-fluorobenzoic acid; 5-Fluoro-2-bromo-4-nitrobenzoic acid; Benzoic acid, 2-bromo-5-fluoro-4-nitro-; 2-Bromo-5-fluoro-4-nitrobenzoic acid; 1805189-72-3; 2-Br-5-F-4-NO2-BA; 2-Bromo-5-fluor-4-nitro-benzoesäure (German); Acide 2-bromo-5-fluoro-4-nitro-benzoïque (French)
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Fluoro-4-Nitro-Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC Area %)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.