Description

(R)-Methyl 2-Amino-3-Methoxypropanoate Hydrochloride is a high-purity chiral building block essential for the synthesis of complex pharmaceutical intermediates. Its defined stereochemistry and functional groups make it a critical reagent for introducing specific molecular configurations in active pharmaceutical ingredients (APIs). This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing novel therapeutics and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of enantiomerically pure drugs, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Peptide Mimetic Synthesis: Used to incorporate methoxy-substituted amino acid analogs into peptide chains for structure-activity relationship (SAR) studies.
• Agrochemical Research: Serves as a building block for developing chiral active ingredients in herbicides and fungicides.
• Asymmetric Catalysis Ligand Precursor: Provides a scaffold for the synthesis of novel chiral ligands used in asymmetric hydrogenation and other catalytic processes.
• Academic & Process Chemistry: Employed in methodological development and scale-up studies for efficient synthetic route design.

Basic Information

Product Name	(R)-Methyl 2-Amino-3-Methoxypropanoate Hydrochloride
CAS No.	1800300-79-1
Molecular Formula	C5H12ClNO3
Molecular Weight	169.61 g/mol
Synonyms	Methyl (R)-2-amino-3-methoxypropanoate hydrochloride; (R)-2-Amino-3-methoxypropionic acid methyl ester hydrochloride; (R)-Methyl 3-methoxyalaninate hydrochloride; Methyl (R)-3-methoxyalaninate hydrochloride; (R)-Methyl β-methoxyalaninate hydrochloride; (R)-Amino-methoxypropionic acid methyl ester HCl; (R)-AMPA methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-Methyl 2-Amino-3-Methoxypropanoate Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.